The Hot Flash Related Daily Interference Scale

Hot flash: TRPV channels in the brain.

TRPV1 (transient receptor potential, vanilloid) channels belong to a family of ligand-gated ion channels gated not only by the binding of certain lipophilic molecules but also by extracellular protons and physical stimuli such as heat or osmotic pressure changes. These nonselective cation channels are permeable to Na(+) and K(+) and are also very Ca(2+) permeable; in fact, TRPV1 is as Ca(2+) pe...

Effect of escitalopram on hot flash interference: a randomized, controlled trial.

OBJECTIVE To estimate the effect of escitalopram (10-20 mg/d) versus placebo for reducing hot flash interference in daily life and understand correlates and predictors of reductions in hot flash interference, a key measure of quality of life. DESIGN Multisite, randomized, double-blind, placebo-controlled clinical trial. SETTING MsFLASH clinical sites in Boston, Indianapolis, Oakland, and Ph...

Impacts of Herbal Medicines on Hot Flash: A Systematic Review

Background: the most common symptoms experienced by women are Hot flashes are around the time of menopause. Many women are interested in herbal medicines because of fear of side effect of Hormone therapy. Objective: In this study, we seek to assess the effectiveness of herbal medicine on the recurrence of hot flash in menopausal women. Methods: The database of MEDLINE, Scopus, and the Co...

Why fixing the furrow does not fix the flash: understanding hot flash biology with botulinum neurotoxin.

Menopausal hormone therapy and national time trends in mortality: cautions regarding causal inference.

877 Validity, cut-points, and minimally important differences for two hot fl ash-related daily interference scales Janet S. Carpenter, PhD, RN, FAAN, Giorgos Bakoyannis, PhD, Julie L. Otte, PhD, RN OCN, Chen X. Chen, PhD, RN, Kevin L. Rand, PhD, Nancy Woods, PhD, RN, FAAN, Katherine Newton, PhD, Hadine Joffe, MD, MSc, JoAnn E. Manson, MD, DrPH, Ellen W. Freeman, PhD, and Katherine A. Guthrie, P...